glp 1 receptor agonist mechanism of action Possible mechanisms of glucagon-like peptide-1 agonists on blood pressure beyond body weight Frontiers | GLP-1 receptor agonist

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INCREASED LEAN MUSCLE MASS & STRENGTH: helps increase lean muscle mass, build strength and decrease body fat

Some of these mechanisms focus on producing reactive oxygen species, glutathione depletion, plasmid curing inhibition, efflux pump inhibition, and resistance enzyme inhibition 46,47

Growth hormone (HGH) then stimulates the liver to produce IGF-1, a powerful anabolic hormone that increases muscle protein synthesis and promotes fat breakdown

This increases the sensitivity to chemotherapy in gastric cancer cells, and offers a novel treatment strategy for advanced gastric cancer and chemotherapy resistance

But more physiologic does not mean no oversight needed. It still warrants a clear rationale, appropriate bloodwork, and monitoring over time