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A medication that works and that you tolerate is more valuable than a theoretically better medication that causes problems during transition

At the time of writing, retatrutide is not yet widely approved for clinical use in the UK

Collagen is the protein responsible for skin strength, firmness, and structure, and stimulating it is key to improving skin laxity without surgery

Additionally, the parenteral route may be the best option for patients experiencing nausea and vomiting

Furthermore, most animal models of DKD rely on chemically induced diabetes, which may inadequately reflect the multifactorial pathophysiology of human DKD (254)

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