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In patients with poorly controlled T2D, 6 months of treatment with liraglutide 1.2 mg/day significantly reduced liver fat content as evaluated by 1 H-magnetic resonance spectroscopy, an effect mainly driven by bodyweight loss (65)
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Secondly, when homocysteine rises, it drives the MS reaction faster, which reduces 5mTHF
31 Moreover, it has been demonstrated that GLP-1 promotes the activation of phosphoinositide 3-kinase (P13K) and protein kinase B (Akt) pathway that favor the survival and function of beta-pancreatic cells
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