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When Selectivity Matters Most: The selective action of AOD-9604 is particularly valuable for individuals with insulin resistance, pre-diabetes, or type 2 diabetes who cannot tolerate glucose elevation, those with personal or family history of cancer who wish to avoid IGF-1 elevation, people seeking pure fat loss without muscle gain or other body composition changes, athletes who need fat loss without anabolic effects or hormonal changes that might affect testing, individuals on complex medication regimens where growth hormones effects would require dose adjustments, and those who prefer targeted interventions over systemic hormonal therapy

doi: 10.1016/j.jgr.2023.11.003 80 WangWLiKXiaoW

Biomarker assessment informs whether supplementation addresses a documented need or represents preventive approach for low-risk individuals

The purpose here isnt to say, Go use these. Its to acknowledge a trend and provide context

Nikiteas NI, Tzanakis N, Gazouli M, Rallis G, Daniilidis K, Theodoropoulos G et al

(2023) 11:e1074