When used alongside GLP-1 receptor agonists, this could theoretically provide additive glucose-lowering effects without increasing hypoglycaemia risk for most patients, as both agents work through glucose-dependent mechanisms
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And because vial, stopper, lyophilisation and assay costs are incurred per vial rather than per milligram, cost per milligram falls as content rises
This is a drug that a doctor prescribes strictly according to indications, and is dispensed in pharmacies with a prescription
Another option that works for some is increasing the dosing interval between injections
Dosing Mounjaro starts at 2.5 mg weekly for four weeks, then increases to 5 mg