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Nature Reviews Molecular Cell Biology, 22 (2), 75-95

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TRIUMPH-2 (1,152 patients with obesity and type 2 diabetes) showed up to 20.8% weight loss and up to 1.6 percentage points of HbA1c reduction at the 12mg dose over 80 weeks

Escalation of Dosing After the initial period, the dose is generally increased incrementally, typically every four weeks, depending on how well the patient tolerates the medication

Some patients even benefit from PlexusDx's GLP-Squared dual-compound option, which combines both mechanisms in a single injection for maximum flexibility

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