Alcohol is not formally contraindicated with semaglutide or tirzepatide, but clinical guidance advises caution because both affect the stomach, blood sugar, and hydration through overlapping pathways
For the appropriate people, it is transformational and can really assist them in having a healthier life. For Peter, who, in addition to wanting to lose weight, also has high blood pressure, high cholesterol, and sleep apnea, its made a big difference
SARS-CoV-2 disrupts host epigenetic regulation via histone mimicry
Verhoef et al, 1994)
These support endogenous GLP-1 release and metabolic health (see emerging science)
They can be useful when an approved drug cannot meet a particular patients needs, but they also carry additional risks