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Pancreatitis occurred in fewer than 1 in 1,000 participants across major semaglutide clinical trials, and rates did not increase with extended exposure

(Jun 1997)

Gut microbiota and oral contraceptive use in overweight and obese patients with polycystic ovary syndrome

J Biol Chem (2002) 277:3626271

In clinical trials of FDA-approved medications used alongside diet and exercise: Participants taking Wegovy (semaglutide 2.4 mg) lost an average of about 15% of body weight over 68 weeks. Participants taking Zepbound (tirzepatide 15 mg) lost an average of about 20% of body weight over 72 weeks. These are average results observed under clinical trial conditions

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