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Traditional GLP-1 weight-loss treatments (such as Saxenda , Ozempic , or Mounjaro ) are typically approved for people with a BMI over 30, or over 27 with medical conditions such as diabetes or high blood pressure

Finally, we outline the implications of adopting semaglutide as a disease-modifying agent in MASH with F2-F3 fibrosis, note the study limitations and remaining questions, and argue that combinatorial approaches targeting complementary metabolic and hepatocentric pathways may define the next phase of MASLD management

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