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In conjunction with earnings, Amgen announced that it has completed an interim analysis of a phase 2 trial of obesity drug candidate maritide (AMG 133)
The most common adverse effects of Wegovy involve the gastrointestinal tract, affecting up to 44% of patients in clinical trials (STEP 1-4 trials)
This is significant because a lower level of hormones could potentially allow ovulation to occur, increasing the risk of an unintended pregnancy
These peptides should be viewed as adjunctive therapies, complementing lifestyle modifications such as dietary changes, increased physical activity, and behavioral counseling
Such approaches greatly affect the generalizability of study results to real-world settings and raise concerns about the validity of projecting the results to long-term outcomes
Bone mineral density in patients with rheumatoid arthritis: relation between disease severity and low bone mineral density
