Postmenopausal women face additional risk due to estrogen deficiency affecting urogenital tissue
WARNING: Not intended for use by pregnant or nursing women or persons under the age of 18. If you are taking any medications or have any medical conditions, including diabetes or hypoglycemia, consult your doctor before use

Symptoms of deep vein thrombosis (DVT) typically affect the legs and may include: Swelling in one leg, ankle, or foot Pain or tenderness, often starting in the calf Warmth in the affected area Red or discolored skin Unexplained leg pain, especially with unilateral symptoms Symptoms of pulmonary embolism (PE) , which occurs when a clot travels to the lungs, constitute a medical emergency and include: Sudden shortness of breath or difficulty breathing Sharp chest pain that worsens with deep breathing or coughing Rapid heart rate or palpitations Coughing up blood Lightheadedness or fainting Symptoms of arterial thrombosis (stroke or heart attack) require immediate emergency care: Sudden weakness or numbness, especially on one side of the body Difficulty speaking or understanding speech Sudden severe headache Chest pain, pressure, or discomfort Pain radiating to the arm, jaw, or back While these symptoms are not specifically associated with tirzepatide, any patient experiencing them should seek immediate medical evaluation regardless of their medication regimen

Lipohypertrophy reduces medication absorption, sometimes by 25% or more, which means the same dose produces less weight loss and less glycemic control
It uses deoxycholic acid to break down fat cell membranes, allowing the body to naturally process and eliminate the fat
August 1, 2025: New Litigation May Form for Zepbound Injuries An increasing number of studies support that GLP-1 drugs like Zepbound increase the risk of an eye disease called NAION (nonarteritic anterior ischemic optic neuropathy)