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Database 2024:113

It also may explain why KPV appears to have a favorable safety profile compared to more aggressive immunosuppressive approaches

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Previous work has shown that the abundance of Lactobacillus reuteri (normalized to a control group) decreases during the onset of obesity and remains suppressed even after dieting in mice 99 , which parallels our observations that vehicle-treated diet-switched mice had lower levels of Lactobacillus than the 5A-1MQ-treated mice, the latter of which also demonstrated greater weight loss

Any discussion of interactions between these two compounds is therefore necessarily theoretical, based on their individual mechanisms of action and general pharmacological principles

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