In STAT3-knockdown MCECs (siSTAT3-transfected), GHK-Cu failed to enhance wound healing in scratch assays (Figures 7A,B) and did not upregulate ZO-1/Occludin expression (Figures 7CF)
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Early research finds some possible actions BPC-157 might have, including: Angiogenesis (new blood vessel growth) Collagen synthesis and fibroblast activity (tissue repair) Nitric oxide regulation (vasodilation and blood flow) Even if BPC-157 caused these effects in humans, we still dont know whether the net effect would be good
This complete absence of tolerability-driven discontinuations represents a remarkable safety finding and indicates that even when mild side effects occurred, they were sufficiently manageable that participants chose to continue treatment
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