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Semaglutide and tirzepatide are often talked about in the same breath because they both help with weight loss and blood-sugar controlbut there are some important differences
Cardiovascular Outcomes in Non-Diabetic Populations The SELECT trial extended this work to a non-diabetic population, reporting that in adults with overweight or obesity and pre-existing cardiovascular disease, semaglutide produced a significant reduction in major adverse cardiovascular events distinguishing the compounds cardiovascular effects from its glycemic activity 4
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Effects of GLP-1-(7-36)NH2, GLP-1-(7-37), and GLP-1- (9-36)NH2 on intravenous glucose tolerance and glucose-induced insulin secretion in healthy humans
