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This rise is partly due to natural aging, but the drop in estrogen also plays a key role, says Chervenak

Additionally, the delayed gastric emptying induced by GLP-1 agonists could theoretically worsen symptoms in patients with stricturing Crohn's disease or those at risk for bowel obstruction
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Treatment with the polysaccharides from okra reduces ROS and MDA while increasing SOD, glutathione peroxidase (GSH-Px), and CAT
