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It can cause side effects such as nausea, vomiting, stomach upset, heartburn, diarrhea, and seizures

Through TGR5 receptor activation, it inhibits STAT3/NF-B/MAPK pathway activation, reduces pro-inflammatory cytokine release, and improves cardiac function parameters at 100 mg/kg doses (Wang et al., 2025)

However, maintaining a calorie-deficient diet is also one of the hardest parts of following a medical weight loss program, as patients are encouraged to continue exercising and will experience increased hunger and cravings

Onset of effects is usually in the range of 30 to 60 minutes post-injection, with peak effects around 1 hour and lasting a few hours in terms of plasma half-life

The compound requires cool, dry storage to maintain molecular stability throughout research

The medication, which has been used off-label as a weight loss aid, has become increasingly popular despite shortages