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The study further proposed that exendin-4 might bind to GLP-1 receptor, mediated by protein kinase A (PKA), and act on the Wnt/-catenin pathway in osteocytes in order to reduce sclerostin expression and promote bone formation ( There are other possible pathways by which GLP-1 could affect bone formation

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J.HalperinM

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Activation of Glucagon-Like Peptide-1 Receptor Inhibits Tumourigenicity and Metastasis of Human Pancreatic Cancer Cells via PI3K/Akt Pathway

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Recovery Peptides and Physical Therapy For musculoskeletal problems, physical therapy and movement-based rehabilitation often remain central

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Importantly, gastrointestinal adaptation is dose-dependent

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