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Individuals with depression may experience increased cravings for high-calorie, high-sugar foods, resulting in excessive caloric intake and subsequent weight gain [35, 36]
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They found people consumed 1.5 fewer drinks per drinking session and had fewer binge drinking episodes
When activated, MC1R triggers a signaling cascade: MC1R activation cAMP increase cAMP activates MITF (master melanocyte transcription factor) MITF upregulates tyrosinase and related enzymes Pheomelanin production shifts to eumelanin production This last point is the key insight
However, the mechanism is plausible
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