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HPLC and LC-MS records serve different documentation roles: HPLC can support peptide purity review, while mass spectrometry can help support peptide identity review when paired with appropriate reference data and batch records [12] [13]

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GHK-Cu, first identified in 1973 from mammalian plasma, functions as a naturally occurring copper-peptide complex that influences approximately 31% of the human genome, resetting gene expression patterns to favor tissue repair while delivering bioavailable copper essential for enzymatic processes underlying collagen synthesis and antioxidant defense

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