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These residues form hydrophobic interactions with the methyl groups, while the carbonyl O of P124 hydrogen bonds with the nitrogen atom, which conforms to a tetrahedral configuration suggesting that it is protonated
Malm-Erjefalt M, Ekblom M, Vouis J, et al
Here, we provide mass spectrometry-based quantitative information about the acyl group- and site-selectivity of all human sirtuins on acylated nucleosomes
Mol Metab 2019;30:72-130
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