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Recently, a high-resolution crystal structure of phosphinic pseudopeptide inhibitor 45 (DG046) in the closed-conformation of ERAP1 was disclosed (Giastas et al., 2019b) and a mechanism for antigen peptide selection by ERAP1 presented (Giastas et al., 2019a)

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A new study found that a popular green tea extract did not cause a reduction in weight compared to placebo, despite the fact that some previous studies have shown a benefit

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Quinolinium ring system: core structure for interacting with the enzyme's active site