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Importantly, this reduction in loading coincided with significant declines in BMD at the total hip ( 7.0%), femoral neck ( 8.8%), and lumbar spine ( 5.2%)
Alcohol also decreases the production and secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), both of which are vital for testosterone production
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Although a trend toward reduced HCC risk was observed, this failed to achieve statistical significance in the overall analysis (IRR: 0.82, 95%CI: 0.61-1.11, P = 0.189), possibly reflecting insufficient follow-up duration to capture the full impact on hepatocarcinogenesis
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