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2037 Physical functioning measures by PROs on MDASI-Lung and 6-minute walk test during first year after chemoradiation and immunotherapy for NSCLC Shu-En Shen 1 , Xin Shelley Wang 1 , Ting Xu 1 , Rachel Maguire 1 , Diana Amaya 1 , Aileen Chen 1 , David Qian 1 , Steven Lin 1 , Anita Deswal 1 , Efstratios Koutroumpakis 1 , Anne Tsao 1 , Mehmet Altan 1 , Mei Chen 1 , Xiaodong Zhang 1 , Ruitao Lin 1 , Jane Pearce 1 , Zhongxing Liao 1 1 The University of Texas MD Anderson Cancer Center, Houston, USA Journal of Patient-Reported Outcomes 2026 , 10(Suppl 1) :2037 Aims Patients with non-small cell lung cancer (NSCLC) may experience significant physical functioning impairment relevant to both disease and toxicities related to concurrent chemoradiation therapy (CRT) and immunotherapy during the first year of survivorship