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This is associated with the opening of mitochondrial channels, the release of cytochrome C, induction of p38 MAPK kinase, accumulation of pro-apoptotic proteins: p53, Bac, and Bax, and reduction in the level of the anti-apoptotic protein Bcl-2 [24]

Not suitable for pregnant or breastfeeding women

Vaginal dryness or discomfort

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