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A larger follow-up RCT (n=72 older adults) confirmed these findings, additionally demonstrating improvements in gait speed (+0.14 m/s), grip strength, 6-minute walk distance, waist circumference reduction, and systolic blood pressure reduction (Kumar et al., J Gerontol A Biol Sci Med Sci, 2023) [21]

Hunger and food intake may increase after treatment stops, and some weight regain is common

Attenuated Nicotine Reward: Research suggests that GLP-1 therapy can reduce the reinforcing properties of nicotine, making smoking less appealing

Whether 1 billion CFU produces enough GABA to meaningfully influence eating behavior is a question the available research does not definitively answer

Study 2 calories and protein (Stachowska et al., 48-hour diaries in 387 adults on GLP-1 or dual GIP/GLP-1 agonists

GLP-1 medications do not directly cause pelvic floor dysfunction, but the straining associated with hard, dry stool can trigger or worsen existing coordination problems