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Safety considerations It is crucial to adhere to the recommended doses to avoid side effects

Based on Phase 2 trial data, the most common side effects are gastrointestinal, including nausea, vomiting, diarrhoea, and constipation, particularly during dose escalation

It becomes oxidized, and then it adds to your bodys oxidative stress burden

The honest version of the economic argument is: we have an evidence gap because the incentives are broken

Interestingly, although mammalian GR somewhat resembles the TrxR domain of SmTGR, the GR domain of SmTGR has the fold of Trx and is appended to the N-terminus of the TrxR core of SmTGR, containing the C28-C31 pair (Figure 1)

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