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Stools may become infrequent and harder to pass

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The modulation of enteric neuronal function and serotonin signaling by GLP-1R agonists contributes to reduced visceral hypersensitivity and pain [52, 53]

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GLP-1 is a hormone produced mainly through the entero-endocrine L-cells of the small intestine that is secreted in response to food intake and is a component of the gut phenomenon known as the incretin effect

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