There are three triggers that can cause dehydration among athletes on GLP-1 meds: Food Deficit: Hydration doesnt just come from fluids you drink
This combination can indicate an obstruction
Phylum-level analyses indicate predominant Firmicutes with relative Bacteroidetes reduction in some studies (264, 265), while others report increased Actinobacteria , Verrucomicrobia , or pro-inflammatory Proteobacteria , alongside potential reduction of beneficial Bacteroidetes and Actinobacteria ( 262, 266)
Bonuses are another core consideration
Expanding an approved drug into an under-served population beats filing a new NDA on cost and speed
In addition, Septerna has the right to opt in to a worldwide profit share for one program in the collaboration in lieu of future milestones and royalties for that product candidate