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PATHOPHYSIOLOGY In the SNc, the two hallmark histopathologic features of PD are depigmentation of dopamine-producing neurons (i.e., loss of SNc neurons) and presence of Lewy bodies (neuronal cytoplasmic filamentous aggregates composed of the presynaptic protein -synuclein) in the remaining SNc neurons

For many people, the proven health benefits of GLP-1s outweigh the potential downsides

(2015) found that perinatal fluoxetine exposure may result in irregular reproductive cycles in adult offspring, as evidenced by a prolonged estrous period, increased numbers of secondary and total follicles, and enhanced apoptosis in ovarian cells

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Global J Med Pharmaceu Biomed Update

The duration of violent behaviors in the socially isolated group receiving normal saline was significantly increased compared to the control group receiving normal saline