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Genome-wide association studies (GWAS) in humans show that the GIPR locus contributes to body weight (BW) regulation and GIPR knockout mice are protected from diet-induced obesity (DIO) 27,28,29,30,31,32

MT-IIs anti-inflammatory properties likely stem from its action on melanocortin receptors (particularly MC1R and MC3R) that are expressed on immune cells, including macrophages and dendritic cells

Inability to lose body fat

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Eligibility depends on health history, current medications, symptoms, labs, and physician review

You might consider vitamin B12 injections, B12 Shots if you are: Following a vegan or vegetarian diet that may not provide sufficient vitamin B12