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For example, clinical trials have shown that less than 5% of participants experienced leg cramps or other muscle-related issues while taking semaglutide

Many patients regain some or much of the lost weight if: diet changes are not sustained physical activity is low emotional eating returns underlying insulin resistance remains the medicine is stopped too early This is especially common if the medicine was doing most of the work and lifestyle measures were not strong enough in the background

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4 In a follow-up study, researchers found that supplementing with vitamins B12 and B9 (folic acid) may increase the risk of colon cancer

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