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For survival analysis, AKP tumour-bearing mice were generated as above, and 26 days after induction, they were treated with 150 mg kg 1 5FU (i.p.) 250 mg kg 1 metformin (o.g.) three times weekly

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The upside: if you can maintain the weight loss, you can often hold on to the health gains too

Be gentle

For a 1.6 mg target dose: Volume to Draw = Desired DoseConcentration = 1.6 mg4 mg/mL = 0.4 mL Convert to syringe units

Mudrick HE, Massey S, McGlinch EB, Parrett BJ, Hemsath JR, Barry ME, et al