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It consists of fifteen amino acids in a unique sequence with no known homology to other natural peptides
Competitive radioligand binding studies reveal nanomolar-range affinities, with the compound effectively displacing radiolabelled VEGF-A in receptor saturation experiments
For example, increased levels of the Egr gene were observed at 1 h, Nos , Srf , and Kras genes demonstrated increased expression at 1 and 24 h in all vessels, and Egr expression was increased at 24 h in both ovarian veins
A practical default is about 28 days in the refrigerator at 2-8 C when mixed with bacteriostatic water and handled cleanly
At the 2.4mg maintenance dose, a 10mg vial lasts only 4.16 weeks, which aligns almost perfectly with the 28-day reconstitution window
Reconstitution: 2.0 mL per 10 mg vial (5 mg/mL) for accurate measurements
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