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Targeted demethylation of specific loci successfully restored sperm count by 80%, confirming that DNA methylation changes represent functional rather than merely correlative alterations (117)
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A variety of neurotransmitter pathways, as well as various peripheral feedback signals, regulate the secretion of GH by acting directly on the anterior pituitary gland and/or by regulating the release of GHRH or somatostatin in the hypothalamus (Moller and Jorgensen, 2009)
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