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After six months, the goal shifts from repair to optimization. Long-term users generally report a higher baseline of health

The performance of each model was compared by examining how close the predicted solutions were to the experimental OCR data using the penalised-likelihood AIC and BIC criteria

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Chen Z and Banerjee R (1998)

Because these compounds are naturally occurring peptides with restricted patentability, opportunities for intellectual property protection and industry-sponsored development are limitedposing substantial barriers to the resource-intensive clinical investigations required to confirm therapeutic efficacy and long-term safety