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Discontinuing the protocol because of manageable discomfort means losing the cumulative biological benefits that GHK-Cu builds over weeks and months of consistent use

This approach introduces dose-response variability that undermines experimental precision, making data interpretation impossible

In the intervention group, three participants were excluded: one voluntarily withdrew and two failed to adhere to the fasting diet based on the food record assessments

"FDA Approves New Medication for Chronic Weight Management." FDA.gov, 2021

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