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Bioinformatics analysis (UbiBrowser) and literature mining were used to predict potential FBXO22-regulated targets, including KDM4A, p53, CD147, PTEN, BAG3, LKB1, KLF4, BACH1, Snail, and HDM2

5-Amino-1MQ (5-Amino-1-methylquinolinium iodide) is a small molecule NNMT inhibitor

This can lead to a B12 deficiency over time

Finally, for recording fatigue levels, the present study adopted BRAF-NRS Question 1 (64) or the 11-point fatigue numeric rating scale (NRS) (65, 66)

In cases where statin therapy does not yield a significant reduction in LDL levels, an LDL-absorption inhibitor can be used, alone or in combination with statins depending on patient response

Lower inflammation