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Middleton D, Pallister J, Klein R, Feng YR, Haining J, Arkinstall R, et al
74 In one randomized, placebo-controlled, crossover trial that included 24 healthy participants aged 55 years and older who had no major sleep issues, 5 mg melatonin 30 minutes before bedtime in controlled experimental conditions increased sleep efficiency, mainly by increasing stage 2 NREM sleep and slightly shortening awakenings