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Choice of control (Control) A pure 2-arm, placebo-controlled, RCT between a single drug and placebo may not be acceptable for prospective participants to be randomised into, given documented multi-systemic benefits of GLP-1 administration

Patients should be aware of symptoms requiring urgent medical attention while abroad, including severe abdominal pain, persistent vomiting, signs of dehydration, or symptoms of pancreatitis or gallbladder disease

When prescribed for weight management, tirzepatide injections are introduced gradually and adjusted based on clinical response and patient tolerance

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Tens of millions of people around the world are now taking drugs like Ozempic a kind of real-time experiment that offers far more data than a carefully controlled clinical trial can

Biochem Biophys Res Commun 2008