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The real question is not: CPAP or GLP-1? The real question is: Which patient phenotype benefits most from each approach and when should we combine them
Jump to: How much weight do people lose on each | How retatrutide and Mounjaro work differently | Side effects compared | What happens if you stop taking the medication | Cost and access in the UK | Cardiovascular and long-term safety | Muscle mass and body composition | Switching considerations | Who should consider which | Frequently asked questions | Take home message | Second Natures Mounjaro programme | References Retatrutide has produced larger weight loss than Mounjaro in trials so far, with an average weight loss of up to 28.7% at 68 weeks in retatrutides TRIUMPH-4 trial, compared with up to 22.5% at 72 weeks in Mounjaros SURMOUNT-1 trial
Loud noises, sudden awakenings, or disruptions to the sleep routine can contribute to night terrors
Lipoatrophy is the opposite, a depression or loss of fat tissue at the injection site, which represents an immune-mediated destruction of adipocytes
People with type 2 diabetes and weight above goal may be candidates for either, depending on clinical presentation
Whatever approach you choose, patience and persistence will serve you well
