The study contributed to a developing preclinical literature suggesting AOD-9604 may have applications in joint and cartilage research distinct from its original metabolic indication
Specifically, the relentless wear-and-tear from reactive oxygen species (ROS) and chronic low-grade inflammation
Anecdotal evidence from athletic and biohacking communities provides supplementary support
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This physiological mechanism, which is useful for the post-translational modification of multiple proteins and for the regulation of signal and metabolic pathways, can turn harmful in case of oxidative stress, with the above-mentioned mitochondrial damage
MOTS-c is generally considered better for anti-aging purposes because it directly targets mitochondrial function and metabolic decline, both of which are central to the aging process