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That diffusion-based nutrition is sufficient for homeostatic maintenance but wholly inadequate for repair

Animal studies have documented significant improvements in Morris water maze performance, radial arm maze accuracy, and novel object recognition tasks, with effects persisting for extended periods after treatment suggesting lasting changes in neural connectivity rather than temporary pharmacological stimulation

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69 Furthermore, the overexpression of claudin-1 in the intestinal epithelium caused hyperactivation of Notch signaling and suppressed goblet cell differentiation and mucin-2 synthesis

Not dangerous but worth noting