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[1] [2] In terms of timeline, early changes in appetite and food intake may be noticed within the first two to four weeks of starting treatment, even at lower starting doses

Compounding gastrointestinal side effects (severe nausea, vomiting, dehydration), increased hypoglycemia risk, unpredictable drug-drug interactions, and complete absence of safety data

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Genetic variants associated with GLP-1 receptor expression and their effects on psychiatric and neurodevelopmental conditions may vary across populations due to differences in allele frequencies, linkage disequilibrium patterns, and environmental exposures

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