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It is also active in the brain, where the receptors it binds to cluster in regions governing reward, motivation and stress the same circuitry that gets hijacked by addiction

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Significant results are often only observed after (mostly unplanned) post-hoc stratification [199, 200], while pre-registered stratified analyses did not show effects [201]

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Diabetes 63, 41864196 (2014)

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This gap between expected and actual appetite suppression often reflects individual differences in how your body metabolizes GLP-1 signals, requiring a personalized assessment rather than a one-size-fits-all adjustment

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