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In conclusion, ERS aggravates the progression of atherosclerosis, while TMAO can selectively bind to the PERK receptor

High-fat meals can slow down the absorption of semaglutide GLP-1 in the body, leading to fluctuating blood sugar levels and potentially compromising the intended benefits of the drug

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Gradual dose titration remains the most effective preventive approach

Compared with DPP-4 inhibitors, the lower rate of hyperkalemia was consistently observed across individual agents in the SGLT-2 inhibitor (canagliflozin, dapagliflozin, empagliflozin) and GLP-1 receptor agonist (dulaglutide, exenatide, liraglutide, semaglutide) classes

Electronic supplementary material Additional file 1: Supplementary Material Model Details for A Mathematical Model of Glutathione Metabolism