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5.4 GIP and GLP-1 effects on lipid and glucose metabolism in adipose tissue and liver Fat and liver are two organs that play key roles in lipid and glucose metabolism, working together in concert and complimentarily to maintain lipid and glucose homeostasis
It is contraindicated in people with Type 1 Diabetes or cancers like Medullary Thyroid Carcinoma and Multiple Endocrine Neoplasia Syndrome Type 2 (MEN 2)
(2010) 298:H156570
doi:10.1016/0006-2952(93)90360-9
Future trials should report age- and disease-stratified data to better clarify whether patient-specific factors, such as diabetes, influence tolerability and safety profiles
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