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J Biol Chem 259:90829089 Nagy-Szakal D, Barupal DK, Lee B, Che X, Williams BL, Kahn EJR, Ukaigwe JE, Bateman L, Klimas NG, Komaroff AL, Levine S, Montoya JG, Peterson DL, Levin B, Hornig M, Fiehn O, Lipkin WI (2018) Insights into myalgic encephalomyelitis/chronic fatigue syndrome phenotypes through comprehensive metabolomics

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When fluids and electrolytes become imbalanced, your brain doesn't function as efficiently, which can contribute to headaches, mental fatigue, and difficulty concentrating

Although the specific mechanism of hemolysis induced by bacterial and viral infection is largely unclear, it has been postulated that phagocytic leukocytes may play a role, through generation of hydrogen peroxide during the phagocytic process (61)

doi: 10.3390/antiox11020251 44