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A total of 1030% of AD patients meet the diagnostic requirements for severe depression (Mann et al

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Common injectable GLP-1 medications used for weight management include: Wegovy (semaglutide) a once-weekly injection approved for chronic weight management

Endocrinology 149(5):20382047

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In people with obesity, 36 weeks of orforglipron (doses ranging from 12 to 45 mg in a phase 2 trial) resulted in a dose-dependent WL up to 14.7% compared to 2.3% with placebo, with concomitant improvement in cardiometabolic risk factors (Table 2) [25]