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Efficacy Estimand Change from Baseline HbA1c, source: Additionally, the 12 mg and 36 mg doses demonstrated clinically meaningful and statistically significant reductions in body weight compared to the placebo

Antioxidants 9:518

Semaglutide pregnancy safety is unknown

At the time of diagnosis of clinical ASCVD in a patient with T2D on a drug regimen that does not include a GLP-1 RA or an SGLT-2 inhibitor with demonstrated cardiovascular benefit