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Collectively, we uncovered a link between hepatic T3 action and glucose homeostasis through GLP-1, and provided evidence to show that the promising results observed for the liver-targeted TR agonist were not secondary to the known beneficial effects of weight loss on insulin sensitivity
The highest doses of medications like tirzepatide have shown even more impressive results, with some patients losing up to twenty-two percent of their initial weight
Regarding L-carnitine supplementation, the current results showed that there was a decrease in the median (IQR) of GI symptoms score in the patients on KD with L-carnitine supplementation in comparison to KD only group indicating clinical improvement in GI symptoms
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Lifestyle therapy consisting of nutrition counseling and physical activity for weight loss was provided for both groups
F.EmhanA.AksoyN.BulutM.et al
